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Term Definition

BRCA2 is a gene that increases the risk of getting breast and ovarian cancer in women and breast and prostate cancer in men.

Out of every 100 women who have a faulty version of this gene, between 80 and 85 will develop breast cancer at some point in their life (80 to 85% lifetime risk). Ovarian cancer lifetime risk is about 27%. Male carriers have an increased risk of breast cancer and prostate cancer.

Definition from Cancer Research UK: BRCA2

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