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Severe combined immune deficiency

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Term Definition
Severe combined immune deficiency

A group of rare inherited disorders that cause severe abnormalities of the immune system. This happens when white blood cells, responsible for fighting infection, are absent, low in number or working poorly. Their absence or poor function results in serious and often life threatening infections.

Definition from Great Ormond Street: SCID fact sheet

SCID can be caused by changes in one of several genes which can be passed on to family members in either an autosomal recessive or X-linked pattern.

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