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Sickle cell disease

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Sickle cell disease

Sickle cell disease is an autosomal recessively inherited disorder of haemoglobin leading to a tendency of red blood cells to deform into ‘sickle’ shapes, especially with dehydration, infection and low oxygen states. This causes a chronic haemolytic anaemia, and recurrent acute painful crises, which can be life-threatening. More often referred to as sickle cell anaemia.

Definition from Genepool: Sickle cell briefing.

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