Text Search

Theme Search

  • 1
  • 2
  • 3
  • 4

Von Hippel Lindau

Search for glossary terms (regular expression allowed)
Begin with Contains Exact termSounds like
All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Term Definition
Von Hippel Lindau

An inherited disorder characterized by the formation of tumours and fluid-filled sacs (cysts) in many different parts of the body. Tumours may be either non-cancerous or cancerous and usually appear during young adulthood; however, the signs and symptoms of von Hippel-Lindau syndrome can occur throughout life.

Von Hippel-Lindau is caused by changes in the VHL gene which normally keeps cells from growing and dividing too rapidly or in an uncontrolled way. A change in the VHL gene can be passed on to family members in an autosomal dominant pattern and increase an individual’s risk of developing tumours or cysts. However, the second copy of the VHL gene must be altered in order to trigger tumour and cyst formation in von Hippel-Lindau syndrome. This second change can occur at any point in a person’s life.

Information from Genetics Home Reference, US National Library of Medicine: Von Hippel Lindau

Tell us your story

We are always looking for new stories to add to this site, and are particularly keen to hear from more practitioners. Your colleagues can learn so much from how you’ve dealt with situations which involved genetics.

Contact Us

Tell us what you think

Your feedback is important in helping us to enhance this website. Please take a moment to complete the brief questionnaire.


Winners of the Association of Healthcare Communicators Best use of new media award 2009.
‘This was superb’ - Judge’s comment.


Betsi Cadwaladr Scholarship Foundation Joint Award Winners 2013.

Betsi Cadwaladr logo